The Science Behind How LSD Works

LSD, or lysergic acid diethylamide, is a psychedelic substance that interacts with serotonin receptors in the brain, particularly the 5-HT2A receptor. This interaction leads to changes in neural connectivity and communication, which can result in the following:

– Enhanced Neural Plasticity:

  Microdosing LSD can promote neural plasticity, the brain’s ability to adapt and form new neural connections. This can improve learning, memory, and cognitive flexibility.

– Altered Perception and Sensory Processing:

  LSD can change the way the brain processes sensory information, leading to heightened awareness and altered perception. In microdoses, these changes are subtle but can still enhance sensory experiences and emotional responses.

– Reduced Default Mode Network (DMN) Activity:

  The DMN is a network of brain regions associated with self-referential thoughts and mind-wandering. LSD can reduce DMN activity, which is linked to a decrease in negative thought patterns and an increase in present-moment awareness.

Why Microdosing Works

Microdosing involves taking very small, sub-perceptual doses of LSD. These doses are not enough to cause the full-blown psychedelic effects associated with higher doses but are sufficient to bring about the positive changes mentioned above. The goal of microdosing is to harness the benefits of LSD without disrupting daily functioning.